Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 386 2,712.05 88.40 269,418,755
Mutual Fund 312 623.62 21.65 64,420,599
Insider 10 13.25 0.44 1,335,735

* Insider values reflect direct beneficial ownership.

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 185 283.78 9.92 30,241,830
Sellers 199 -286.77 10.16 -30,955,017
Net -2.99 0.23 -713,187

Concentration

Value ($MM) % O/S Shares
Total Inst. 2,727.33 88.98 271,199,427
Top 10 Inst. 1,742.20 54.48 166,049,304
Top 20 Inst. 2,093.81 66.77 203,493,804
Top 50 Inst. 2,437.81 78.77 240,064,678

Style

Holders Value ($MM) % Inst Shares Shares
Growth 84 307.02 10.70 32,616,401
Aggressive Growth 6 18.00 0.56 1,711,490
Core Growth 57 246.83 8.67 26,410,930
Growth 21 42.20 1.47 4,493,981
Income 9 7.55 0.26 796,684
Income Value 4 5.29 0.18 563,458
Yield 5 2.26 0.08 233,226
Index 32 697.61 24.38 74,308,504
Other 127 1,556.79 48.02 146,344,134
Broker Dealer 23 121.13 4.23 12,899,935
GARP 38 154.12 5.39 16,415,482
Hedge Fund 59 539.05 18.84 57,431,752
Specialty 3 5.83 0.21 634,548
VC Private Equity 4 736.66 19.35 58,962,417
Value 47 82.96 2.95 8,988,885
Core Value 38 52.28 1.87 5,711,565
Deep Value 9 30.69 1.08 3,277,320

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Quogue Capital L.L.C. 28,067,333 9.21 5,000,000 2/20/24
The Vanguard Group, Inc. 27,272,786 8.95 1,363,323 9/30/24
Perceptive Advisors LLC 26,617,709 8.73 684,567 9/30/24
MHR Fund Management LLC 23,997,103 7.87 -- 9/30/24
BlackRock Institutional Trust Company, N.A. 18,708,984 6.14 159,746 9/30/24
State Street Global Advisors (US) 13,201,978 4.33 576,801 9/30/24
Soleus Capital Management, L.P. 8,528,500 2.80 980,500 9/30/24
Hood River Capital Management LLC 8,144,637 2.67 5,412,210 9/30/24
T. Rowe Price Investment Management, Inc. 5,861,279 1.92 3,810,779 9/30/24
Geode Capital Management, L.L.C. 5,648,995 1.85 -137,537 9/30/24

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 8,671,292 2.85 -41,251 10/31/24
SPDR S&P Biotech ETF 7,027,422 2.31 -173,702 11/30/24
iShares Russell 2000 ETF 7,024,099 2.30 482,080 11/30/24
Vanguard Small-Cap Index Fund 6,844,849 2.25 13,400 10/31/24
Vanguard Small-Cap Value Index Fund 4,628,737 1.52 -1,596 10/31/24
Hood River Small-Cap Growth Fund 4,575,551 1.50 3,166,967 9/30/24
Vanguard Extended Market Index Fund 3,361,245 1.10 -21,421 10/31/24
Macquarie Small Cap Core Fund 2,611,822 0.86 -- 10/31/24
Fidelity Small Cap Index Fund 2,587,803 0.85 10,167 10/31/24
iShares Russell 2000 Growth ETF 2,282,233 0.75 21,352 11/30/24

Location: Global Region

Holders % O/S Shares Share Change
North America 296 82.27 250,755,117 --
Europe 77 6.02 18,342,956 --
Asia / Pacific 22 0.69 2,088,928 --
Africa 1 -- 12,136 --
Latin America 1 -- 353 --

Location: Country

Source: LSEG